Wednesday, August 28, 2013

Carcinoma Esophagus 1 Causes Incidence Pathology


4.3 CARCINOMA OF OESOPHAGUS

The incidence of this disorder is variable.

-  In  the  United  States,it varies from  5  cases  per  100,000   

   population in whites to 20 per 100,000 in blacks per year.

-  The incidence is very high in the areas around the Caspian sea   

   North China and Russia.

-  In India the incidence is high in Kashmir and Assam.

The etiology is related to certain factors  principally :

*  Alcohol intake

*  Tobacco use

*  Malnutrition

*  Vitamin deficiency

*  Anaemia and

*  poor oral hygiene.

 

Intake  of  hot food and bevrages have also  been  implicated  in

India.

 

PATHOLOGY

 

  - The  lesion occurs most often (50%) in the mid third  of  the

    oesophagus,  about  a third of the case occur  in  the  lower

    third and upper third is involved in less than 20%

 

  - The lesion is most often (90%) a squamous cell carcinoma  but

    adenocarcinomas can occur at the lower end.

 

  - The tumour spreads through the wall of the oesophagus to  the

    adjoining structures. 

 

  - Spread to regional lymphnodes is also common.
 
Any Questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review.
Visitors that follow may post contrbutions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com

Wednesday, August 21, 2013

Esophageal disorders benign 4 Tumors



4. TUMOURS

4.1 LEIOMYOMA

 

This  is the most common benign tumour of the  oesophagus.   They

occur in equal frequency in males and females between the ages of

20-50  years.  The majority of these intramural tumour  occur  in

the middle and lower thirds of the oesophagus.

 

They  present  with  dysphagia  small (<5 cm="" span="" style="mso-spacerun: yes;"> 
and  may  have  no
symptoms.  Obstruction and regurgitation occurs in large tumours.

 

TREATMENT

 

The tumour is excised through a thoracotomy (left for lower third

and  right  for  middly  third).   The  longitudinal  fibres   of

oesophagus  split  and the tumours dissected out  -  leaving  the

submucosa intact.  The longitudinal fibres are stiched.

 

4.2 HEMANIGIOMAS

 

These  constitute  2-3%  of all benign  tumours  and  may  remain

symptomless.   They may sometimes cause  successive  hematemesis. 

Laser  therapy through the endoscope provide effective  means  of

treatment.
 
Any questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review.
Visitors that follow may contributions to the site.
To create comsumer/provider engagement visit www.drmmkapur.blogspot.com

Wednesday, August 14, 2013

ESOPHAGEAL Disorders Benign 3 Hiatus Hernia


3.4 HIATUS HERNIA

This  is  a  herniation of the stomach  through  the  oesophageal

hiatus of the diaphragm.

- Type 1 hernia is the more common variety and allows the stomach

  to slide up into the thorax (Sliding hernia)Fig. 15.7

The symptoms are of retrosternal burning after a heavy meal or on

lying down, these symptoms are because of reflux of acid  gastric

content into the oesophagus.

The  acid  gastric  content causes oesophagitis,  the  hernia  is

diagnosed  on  radiology  (barium study) and if  the  patient  is

symptomatic, requires treatment for oesophagitis.

Type  II  hernia  is  rare and also referred  to  as  rolling  or

paraoesophageal hernia,this is a true hernia and has a peritoneal

sac.  Fig. above

Symptoms  of  reflux  are usually absent and in fact  it  may  be

completely asymptomatic.

If  symptomatic  the patient complains of fullness  after  meals,

dysphagia,there may also be stasis. 

Treatment  involves surgical reduction of the hernia excision  of

the sac and repair of the defect in the diaphragm.

 

TREATMENT OF REFLUX : Medical

To reduce regurgitation

*  Elevation of Head end of bed

*  To reduce evening meal size

*  To sleep at least two hours after last meal of the day

*  Antacids to be taken 1 hour after meals

*  Cimetidine may be tried to reduce gastric acidity

 

SURGERY (ANTIREFLUX)

Surgery  is aimed at creating a valve mechanism at the cardia  by

wrapping  the  stomach  around  the  oesophagus  in  the  abdomen

(Nissens)

 

 

Operative correction of esophageral hiatal hernia should

-         return the herniated content to its anatomically correct position below the diaphragm

-         repair the hernia defect

-         prevent recurrence while mainimizing associated morbidity.
 
Any questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review.
Visitors that follow may post contributions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com

Wednesday, August 7, 2013

Esophageal disorders Benign 2


3.2 PHARYNGOESOPHAGEL DIVERTICULUM

This  is a mucosal pouch between the inferior constrictor of  the

pharynx and criopharyngeus muscle (UES) (Fig.above).

- The patient is between 30-40 years of complaining of  dysphagia

  at the upper end of oesophagus.

- An effortless regurgitation of undigested food.

- There may be gurgling in the neck and

- Some patients compalin of choking and aspiration.

Diagnosis  is made with a barium study and treatment is  surgical

with  excision of the divertication and repair of the  defect  in

the muscle.

 

3.3 PLUMER VINSON SYNDROME (PATERSON-KELLY)

This is a cervical dysphagia in women above the age of 40 years

- These patients have iron  defieciency  anaemia. 

- They manifest atrophic oral mucosa., 

- The  cause   of  dysphagia  is  sometimes  the   presence   of

  demonstrable oesophageal web.

Treatment is with dilatation and correction of the anaemia.
 
Any questions be sent to drmmkapur@gmail .com
All older posts are stored in archives for access and revirw
Visitors that follow may post contributions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com

Wednesday, July 31, 2013

Esophageal disorders Benign 1 Achlasia



3. BENIGN DISORDERS

3.1 ACHLASIA CARDIA

There  is in this disorder a failure of relaxation of  the  lower

end of the oesophagus (LES).

-  The etiology is unknown.

-  There is evidence  of  vagus nerve dysfunction and an observed

   change in morphology and number of oesophageal ganglion cells

   of  Auerbach's plexus.  There is progressive dilation  of  the

   oesophagus

-  The presenting symptoms of this disorder are food sticking and

   patients using fluids to wash down the food.

-  The sticking  or dysphagia may be referred to the suprasternal

   notch and may be made worse by stress.

-  There may  also  be a complaint of regurgitation or eructation

   of foul odour.

-  In cases there is a loss of weight.

-  Pulmonary  complication occur  because of aspiration pneumonia

   and include lung abscess, bronciectasis and haemoptysis.

Diagnosis  is  established  with  a  barium  study  which   shows

dilation,  tortuosity  of proximal esophagus and bird  beak  like

narrowing  of  the terminal portion of the oesophagus Roesophagus

copy is indicated to rule out oesophagitis and carcinoma

 

 

Esophageal manometry remains best for diagnosing achalasia, absent peristalsis in the distal smooth muscle segment of the esophagus with incomplete LES relaxation. In cases of manometric finding of normal esophageal motility an aggressive search for a tumor must be undertaken.

 

 

Treatment is surgical and involves an incision into the  muscular

coat  of  the terminal portion of narrow oesophagus  leaving  the

mucosa  intact  (oesophagomyotomy) (Fig. above.   Dilation  with

hydrostatic   or  pneumatic  dilators  can  be  tried.   Use   of

nitroglycerin sublingual can provide temporary relief of swollowing

difficulty

 

 

The drugs used to treat patients with achalasia have been smooth muscle relaxatnts aimed at decreasing LES tone, are calcium channel blockers (nifedipine, verapamil), opiods (loperamide), nitrates (isorsorbide dinitrate), and anticholinergics (cimetropium bromide) pharmacotherapy is best reserved as an adjunct to other therapies.

 

Botulinum toxin (BoTox) is a potent inhibitor of acetylcholine release form presynaptic nerve terminals. Recently, BoTox endoscopically injected into the LES has been used in the management of achalasia to decrease resting LES tone.

Heartburn relieve ingesting antacid regurgitation dysphagia.

Short term treatment acid suppression regimens effectively relieve symptoms

Any questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review
Visitors that follow may post contributions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com
www.otmanage.blogspot.com

Wednesday, July 24, 2013

Esophageal disorders acquired corrosive strictures


3.ACQUIRED

The acquired disorders may present in childhood or in adult  life

and  manifest  most  often  with  complaints  of  difficulty   in

swallowing(dysphagia).

 

  * The complaint  may  follow  a history of having  swallowed  a

    chemical   (corrosive  stricture)  or  it  may  be   a   slow

    progressive   dysphagia   (aclasia,   reflux    oesophagitis,

    carcinoma)

 

  * The  other  complaints  in disorders of  the  oesophagus  are

    related to the under nutrition as a result of the dysphagia.

 

  * The retained contents of the oesophagus can also be aspirated

    into  the  lungs  resulting  in  infection  and   respiratory

    insufficney.

 

2.2.1 CORROSIVE STRICTURES

These are caused by alkalies (sodium hydroxide, sodium carbonate)

and acids (hydrochloric, nitric, sulphuric) they are used in  the

households for cleaning purposes and may be accidently  ingested.

   - In  these  cases strictures may form at any  site  from  the

     oropharynx  to  the  small intestines  in  addition  to  the

     oesophagus.

 

   - It  is  important  that the chemical be  identified  by  the

     history,  examination of the container or from  analysis  of

     the contents of the container.

 

  * Neutralisation  can only be possible if the patient  is  seen

    within the hour after ingestion.

  * Inducing vomitting or gastric lavage are contraindicated.

  * If the patient has stridor, hoarseness dyspnoea or shows sign

    of  burns  in  the mouth and pharynx the  patient  should  be

    admitted.

  * To prevent excessive inflammation and oedema treatment should

    be started with antibiotics and steroids.

  * In  cases of increasing  respiratory  difficulty,tracheostomy

    may be required.

  * X-ray of the chest and abdomen should be studied for evidence

    of  perforation into the mediastinum and into the  peritoneal

    cavity (air leak)

On diagnosis of burns further treatment consists of :

  * Medical treatment with antibiotics and steroids (3 weeks)  to

    minimise fibrous tissue laying down and

    Dilation and splinting of the burn segment so as to  maintain

    the lumen of the oesophagus

In cases where inspite of above regime strictures form.

  * Gastrostomy may be required to maintain nutrition.

  * This is followed by dilatation using direct visualisation  of

    the  stricture  through an  oesophaguscope  or  alternatively

    retrograde dilatation through a gastrostomy.

  * Savary-Gilliard bougies are another dafe method.  A guide wire

    is  introduced through the instrument channel of  a  flexible

    esaphagoscope.  The scope is then removed and savary dilaters

    threaded over the guide wire.

 *  In   some   cases   of   extensive   persistent   strictures,

    reconstrcution  of  oesophagus by  interposition  of  colonic

    segment may be required.

 

 

Operative intervention is indicated when

-         there is complete stenosis in which all attempts at dilatation have failed

-         severe periesophageal reaction or mediastinitis develops with dilation

-         a fistula forms

-         the patient is unable to undergo repeated dilation for a prolonged period of time
 
All questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review.
Visitors that follow may post contributions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com
 

Wednesday, July 17, 2013

Esophageal disorders Congenital

2. DISORDERS OF THE OESOPHAGUS
 
2.1 CONGENITAL
 
ESOPHAGEAL ATRESIA
A  developmental defect is because of incomplete canalisation  of
esophagus. 
The defect is suspected on first feeding of  the  new
born.
 - There is choking coughing and cynosis on feeding.
 - There are five varieties of the observed defects as  shown  in
   Fig The variety C is the most common (85%).
 - The  diagnosis is  established by passage of  rubber  catheter
   through the nose and confirming the obstruction.
 
*  AP & Lat chest Xray will give the level of obstruction.
*  If Xray shows gas in GI Tract or Tracheo-Esophageal fistula is
   suspected .
 
TREATMENT
*   Pump suction of proximal pouch
*   Immediate assessment for other congenital defects
*   Surgical repair of the defect
 
Any questions be sent to drmmkapur@gmail.com
All older posts are stored in archives for access and review.
Visitors that follow may post contributions to the site.
To create consumer/provider engagement visit www.drmmkapur.blogspot.com