Thursday, June 7, 2012

ONCOLOGY 9 tumor markers



SPECIFIC MARKERS                                      



9.1 Carcino embryonic antigen (CEA)



This  marker correlates well with the  presence of  carcinoma  in

the gastrintestinal tract especially mentioned in relation to  Ca

of  colon.   Na marker is available for oesophagus,  Stomach  and

pancreatic carcinoma.



Ovarian  CA  125  is  most  reliable  for  diagnosis  of  ovarian

carcinomas  Prostate carcinoma, Prostatic specific antigen  (PSA)

is useful marker for detecting prostate carcinoma



9.2 Hepatocellular Carcinoma



Serum  alpha feto protein (AFP) in 50-80% of patients with  liver

carcinoma, this marker is positive



Carcinoids 5 hydroxindole-acetic  acid (5HIRA)  is  useful  for

diagnosis and management of this tumour.
Fall in level of marker is indication of good response to treatment.

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