Wednesday, July 29, 2015

Cancer Pancreas 2 Clinical


7.2 CLINCIAL MANIFESTION

Periampullary  carcinomas  of the head of  the  pancreas  present
with:

*  Jaundice with a palpable gall bladder (Courvoisier's law)
   Fig.22.3)
*  Pain
*  Weight loss and a mass

7.3 CARCINOMA OF BODY

Radiation  of pain to the back is seen in both carcinoma  of  the
head and body.

*  Pain is extremely frequent in carcinomas of the body and tail
*  Progressive  jaundice,  anorexia and weakness  are  the  other
   presentations
*  Diarrhoea, constipation and pruitis may also be seen
*  In jaundice cases, chills and fever are common

7.4 DIAGNOSIS

Investigations  for jaundice and other liver function  tests  are
required.

An ultrasound or CT may help to establish the diagnosis.

An  endoscopy  to  view  the ampulla of  vater  and  an  ERCP  to
demonstrate the anatomy of biliary and pancreatic ducts can  also
help the diagnosis

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Wednesday, July 22, 2015

Tumors CANCER PANCREAS 1


TUMOURS                       PANCREATIC CARCINOMA                    
                                                                     Common presenting features              
CARCINOMA OF THE PANCREAS           * Substantial weight loss               
                                                                             (about 80%)                           
Average  age of  patients                                  * Abdominal pain(about 60%)             
with  adenocarcinoma   is                                 * Obstructive jaundice,                 
sixty years.                                                       often without pain                     
                                                                         (about 50%)                           
Ninty     percent      of                                   Less common features                    
adenocarcinomas are  from                             * Acute pancreatitis(15%)               
the  exocrine   secreting                                  * Diabetes mellitus                     
ductal   cells   of   the                                        (preceding for following              
pancreas  about  5%   are                                   carcinoma)                            
tumours    of    acinenon                                * Gastric outlet obstruction            
exocrine cells, about 20%                                    (due to external                      
are   tumours   of    the                                          compression)                          
endocrine   islet   cells                                    * Thrombophlebitis migrans              
these manifest by secreting excess hormones(insulin, glucogon  or
gastrin)
Males are frequently affected
Cause is unknown

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Tuesday, July 14, 2015

Cysts Pancreas 1


 CYSTS

Three-quarters  of  all  cystic  lesions  in  the  pancreas   are
pseudocytsts.

Pancreatitis and trauma are important causes of pseudocysts.

*  In  a pseudocyst a fibrous tissue wall surrounds a  collection
   of escaped pancreatic juice (with or without a blood clot)

*  They are unilocular and situated in the lesser sac.

*  Occasionally  they  occur within the  pancreas  or  transverse
   mesocolon

*  They  result  from a disruption of the ductal  system  of  the
   pancreas.

CLINICAL MANIFESTATIONS :

Presistant pain, fever and ileus appearing 2 to 3 weeks after  an
attack of pancreatitis or trauma are the main symptoms.

-  Pain is in the epigastrium or left upper quadrant
-  A mass is felt on examination
-  Nausea, vomiting or anorexia may also occur

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Tuesday, July 7, 2015

Trauma PANCREAS


TRAUMA

Penetrating  trauma  like in gunshot or stab wounds is  the  main
cause.

Blunt  trauma  is responsible in a third of cases and  tears  the
pancreas in two across the vertebral column. Fig. 22.2

*  Patients present with history of trauma
*  Followed by signs of blood loss, peritonitis and shock
*  Pancreatic fistula, pseudocyst or death are usually the result
   of  disruption  of the organ itself or its  ductal  system  in 
   late undiagnosed case.
*  Awareness  of the possibility of this should be kept  in  mind
   when trauma is followed by abdominal pain
   -  evidence of continuing haemorrhage
   -  tenderness and guarding or
   -  fever

5.1 TREATMENT

At the time of exploration of the haematoma, attention should  be
first  directed  towards haemostasis followed by  repair  of  the
injury.

In some cases distal pancreatectomy is required.

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