SPLEEN FUNCTION 3 hypersplenism hyposplenism

3. HYPERSPLENISM

The  term hypersplenism is used when there is a reduction in  the

circulation of :

*  Red cells

*  White cells or platelets

*  Any combination of these elements

*  There is in addition bone marrow hyperplasia and splenomegaly

Some  of  the case that may be causes responsive  to  splenectomy

are;

-  Lymphcoma

-  Chronic lymphatic leukemia

-  Hairy cell leukemia

Hyersplenism also occurs in;

-  Portal hypertension

-  Malaria, Kala-azar

-  Sarcoid

-  Lipid storage desease

These  patients  present with symptoms related to  the  deficient

cellular component i.e. anaemia or ecchymosis

Some patients do well after splenectomy

4. HYPOSPLENISM

Hyposlenism  occur  in cases of congenital absence of  spleen  or

splenic infarcts (sickle cell anemia)

This  complication  results in sepsis due to  deminished  splenic

function

It is sometimes seen after splenectomy

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