Renal Transplantation 4 post operative

POST-OPERATIVE MANAGEMENT

Patients  are usually nursed in isolation for the first 48  hours

after  operation  and careful isolation and  barrier  nursing  is

essential.

*  Kidneys  with a  short warm ischaemic  time  usually  function

   immediately after transplantation

*  In this situation, biochemical estimations are the mainstay of

   the diagnosis of rejection

*  The  serum creatinine , creatinine clearance  and  blood  urea

   should be estimated daily

*  Of these, the  serum creatnine is the most reliable  index  of

   rejection

*  Confirmatory clinical signs are often present

These include graft swelling and tenderness:

-  A reduction in urine volume

-  Pyrexia

-  Unexplained weight gain or

-  A rise in blood pressure

*  Isotope  techniques such as gamma  camera  sintiscanning,  the

   uptake of 125I fibrinogen and the injection of Indium labelled

   autologous  platelets have all been used to give arly  warning

   of rejection

*  The  urine  may  also be tested  for  the  presence  of  cells

   fibrin/fibrinogen  degradation products and  specific  urinary

   enzymes such as N-acetyl glucosaminidase.

Any questions be sent to drmmkapur@gmail.com

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