HYPERKERATOSIS
White patches are sometimes seen on oral mucosa called
leukoplakia.
This is a specific premalignant lesion.
* Microscopic change show hyperplasia, keratosis and
dyskeratosis, i.e. loss of normal stratification, irregularity
in the size and shape of cells, abnormal staining
characteristics.
* Palpation will reveal a definite firmness of the mucosa.
* Cancer will develop in 5% of such patients.
* Local irritant associated with this lesion are smoking, sepsis,
sharp tooth, spirits and spices (in betel chewing) these
should be eliminated.
Local excision may be useful.
Radiation therapy is contraindicated.
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