8. RELAXANTS
Muscle relaxants given intravenously can cause profound muscular
relaxation without increasing the depth of anaesthesia.
* It is to be noted that these patients will have inability
to maintain ventilation because of relaxation of
respiratory muscles.
* This can be compensated for by artificial ventilation to
maintain normal arterial oxygenation and normal carbon-
dioxide excretion.
* There are two varieties of muscle relaxants.
- Curare which interferes with transmission of impulse
at the myo-nural junction by competing with
acetylcholine at the motor-end plate(Non-depolarizing).
They are longer acting.
- Succinylcholine: These interfere with myo-neural
transmission by producing depolarization of the end-
plate.These agents are shorter acting.
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