Diagnosis
1. In cutaneous lesions, dark field examination of
discharge from
skin lesions for
treponema pallidum.
2. Demonstration
of treponema pallidum
in tissue on
histopathological
examination.
3. Serological
tests : The value
of these tests in
various
stages of the
desease is given in table 28.1.
Table 28.1:
Percent Positivity of Tests
_________________________________________________________________
Test Primary Secondary
Latent Tertiary
_________________________________________________________________
VDRL
72 100 73 77
Flourescent
91 100 97
100
Trepenoma Antibody
FTA-ABS
Trepenoma Pallidum
46 98 95 95
Immobilisations (TPI)
Haemoaglutination
69 100 98
100
_________________________________________________________________
1.5 Treatment
Penicillin-G is a
drug of choice for all stages of syphilis.
T-
Pallidum is killed
by low doses
of penicillin G;
other
antibiotics
effective in syphilis
include tetracycline,
erythromycin and caphalordin.
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