Saturday, April 29, 2017

Std Yaws clinical treatment

Yaws
This  disease  is  seen  in  the  tropical  countries.  Causative
organism  is Treponema pertenue which  appears  undistinguishable
from  T.  Pallidum.  It  is  discussed  here  because  of   these
similarity.
*  It is acquired by direct non-sexual contact
*  The first lesion is an ulcer on the skin leaving a thin  scar.
   Skin rashes occur in 1-3 months after the primary infection
*  The  tertiary  lesions are again like syphilis with  skin  and
   bone lesions are common.

 Treatment
Penicilin  provides  effective  treatment  for  the  disease  2.4
millions  units, Penicillin-G intramuscularly in adults  provides

rapid resolution of the lesions.

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Monday, April 24, 2017

Sexually transmitted deceases Lymphgranuloma inguinale

LYMPHGRANULOMA INGUINALE
This  venereal  disease  occur  in  the  tropical  climates.  The
causative  agent is Chlamydia trachomatis. The incubation  period
is  3-90  days. The lesion produced is an ulcer on  the  genitals
which  is followed later by swellings of the inguinal  nodes.  In
women,  vaginal  or anal infection can occur followed  by  rectal
strictures  because  of  spread of  the  inflammation  along  the
pararectal lymphatics.

4.1 Diagnosis
Is  made by demonstration of Chlamydia from the discharge of  pus
from  the  lymphnodes. Frei skin tes  and  microimmunofluoroscent
test if available can be used

4.2 Treatment
Tetracycline (500 mg. O.D.), Sulphonamide (1 gm QID) are used  in

the treatment of this condition

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Monday, April 17, 2017

Gonoccocal infection diagnosis treatment

Diagnosis
1. Gram  stain  of  urethral or endocervical  exudate  show  gram
   negative diplococci
2. Later  obtaining the secretions by prostatic massage may  give
   information  on  presence  of chronic infection  due  to  this
   diplococcus

2.3 Treatment
A  combination  of ampicillin 3-5 gms. single  dose  followed  by
doxycycline  100 mg. twice daily for seven days is  effective  in
the majority of gonococcal infections.

After  treatment, it is important to show that the infection  has
been cured. Urethral secretions are examined in men.
Treatment  of  strictures  is with  dilatation  is  discussed  in

chapter 29.

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Monday, April 10, 2017

Gonococcal Infection Clinical

GONOCOCCAL INFECTION
The infecting organism is Neisseria Gonorrhoeae. A gram  negative
kidney shaped diplococcus which affects the urethra of both sexes
and the cervix in the females.

2.1 Clinical Features
Gonorrhoea is purulent infection of the urethra and less often of
the rectum and vigina
*  Rarely it is met with as conjunctivitis of the new born
*  It presents  most often with burning mucturition in  the  male
   followed  by  discharge  of  yellowish  pus  2-10  days  after
   intercourse with an inffected person
*  Infection  may  also  pass  proximally  and  cause  prostatits
   vesiculitis  and  epidydimoorchitis  in the  male.  All  these
   sequelae  bring the male patient to the surgical out  patients
   department
*  Damage  of the  wall of the urethra may lead to  fibrosis  and
   urethral stricture later.
*  In women;  the infection may lead to Salphingitis,  cellulitis
   and  infection of Bartholins' glands: A late  complication  is
   sterility.  Uncommon  late  complications  of  gonorrhoea  are

   synovitis and arthritis.

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Monday, April 3, 2017

STD Syphilis diagnosis Treatmrnt


Diagnosis
1. In cutaneous lesions, dark field examination of discharge from
   skin lesions for treponema pallidum.
2. Demonstration   of   treponema    pallidum    in   tissue   on
   histopathological examination.
3. Serological  tests  : The  value  of these  tests  in  various
   stages of the desease is given in table 28.1.

Table 28.1:  Percent Positivity of Tests
_________________________________________________________________
Test                    Primary     Secondary   Latent   Tertiary
_________________________________________________________________
VDRL                     72           100         73       77
Flourescent              91           100         97      100
Trepenoma  Antibody
FTA-ABS
Trepenoma Pallidum       46            98         95       95
Immobilisations (TPI)
Haemoaglutination        69           100         98      100
_________________________________________________________________

1.5 Treatment
Penicillin-G  is a drug of choice for all stages of syphilis.  T-
Pallidum   is  killed  by  low  doses  of  penicillin  G;   other
antibiotics   effective   in   syphilis   include   tetracycline,

erythromycin and caphalordin.


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