PATHO-PYSIOLOGY(CONT)
* Red cells are lost in deep burns due to the effects of
heat, increased fragility and stagnation and sludging occurs in the
capillary bed.
This may be to the extent of 8 to 12% of RBC mass per day.
* There is an effect produced on the GI tract.
Ileus is always there in cases of over 25% burns of fluid treatment
is provided motility returns in 3-5 days.
Mucosal damage due to local ischaemia.
These areas may go on to become ulcers if untreated.
* Endocrine changes occur in the form of raised glucugon
cortisol and catacholamine levels.
Insulin and T3 levels are depressed.
* Immune response is also depressed.
This shows as reduction of lymphocytes 48 hours after the burns.
Thus infection occurs, serum globulin are also reduced, and return to normal
in 2-4 weeks.
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