Wednesday, May 4, 2011

TETANUS 2




Nature of Wounds

Wounds superficial or deep may be contaminated with Cl. tetanus in street accidents.
However, a prerequisite for multiplication of Cl. tetanus is the
presence of a LOW OXYGEN tension within the wound.
Rarely, organisms may be lodged in an old healed wound and RE-
INJURY of the same area may produce the required conditions of
low oxygen tension.

In India, tetanus is also met with post abortion, and after
delivery period, in woman.
It may effect the new born, and is referred to as tetanus
NEONOTARUM.(80,0000 deaths per year worldwide)
In many countries, infection is also occurs among narcotic
addicts, since they inject themselves with drugs under less than
ideal conditions.
Symptoms of the disorder are the result of an exotoxin (tetnospasmin)
that travels along the nerve sheaths to the central nervous
system,
It lowers the threshold of excitability of the
motor neurone cells.

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