5.1 PROTEINS SYNTHESIS
As the hepatic cell is responsible of
synthesis of
- albumin,alfa feta protein,
cereloplasmin, ferritin and
Transfenin
- fibrinogen
- prothrombin and other factors
involved in blood clotting I,
II, V, VII, IX, X, XI, XII, XIII
Estimation of serum albumin is the most accurate relfection
of
liver function.
*
Half life of albumin is more than 10 days
*
Flocculation and Turbidity Tests are dependant on albumin and
thus;
- Cephalin flocculation
- Thymol turbidity
- Zinc sulfate turbidity
tests are reflections
of the
alteration in the albumin globulin ration in the serum
5.2 CARBOHYDRATES AND LIPIDS SYNTHESIS
Syntehsis of both phospholipid and
cholesterol takes place in the
liver
and the latter
serves as an indicator for
the lipid
metabolism
*
Biliary obstruction results in a rise in cholesterol
*
The other common effects of hepatic disease is a deficiency of
glycogenesis with resultant hyperglycemia
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