CLINICAL MANIFESTATIONS
The
clinical presentation is of abrupt onset in about one-third
and may run a fulminant course in 10%.
*
Persistent diarrhoea, preceded by
lower abdominal cramps is
the usual complaint.
*
Small stools recurring 20 to 30 times per day.
The diarrhoea produces
*
Dehydration
*
Hypokalemia
*
Anaemia
*
Hypoproteinemia
*
Marked weight loss
*
Relapsing form with remissions is
also common. Recurrences
are associated with
emotional stress, physical
fatigue,
respiratory infections and other acute illness.
*
Lower abdominal cramping is always present.
COMPLICATIONS
*
Electrolyte deficiencies
*
Microcytic anaemia
*
Arthritis
*
Arthralgias
*
Spondylitis
Colonic complications include gross
haemorrhage
*
Stricture formation
*
Partial obstruction
*
Perforation may occur in the course of the disease
LATE COMPLICATIONS
Late complications also include toxic
megacolon and carcinoma of
the colon.
DIAGNOSIS
Colonoscopy Sigmodoscopy including
rectal biopsy and
Barium enema are
important in arriving at a diagnosis
(Fig. 19.2).
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