Tuesday, March 17, 2015

PERITONITIS Pathology


ACUTE PERITONITIS

3.1 PATHOLOGY

Contamination of the peritoneum with intestinal content  produces
both chemical and becterial peritonitis.

The  inflammatory response consistes of dilatation of  the  small
vessels   of   the   peritoneum  and   an   increased   capillary
permeability.

-  There  is increased fluid exudation both into  the  peritoneal
   cavity and in the submesothelial space (third space) producing
   oedema and thickening of the peritoneum.

-  The exudate contain phagocytes and fibrin
  
-  This fibrin content tends to cause adhesion between  adjoining
   inflammed peritoneal surfaces.

-  The  peritoneum loses its shine and may even be  roughened  on
   the surface.

-  The sequestration of fluid in the third space causes a  series
   of body changes that can threaten the life of the patient.

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