Cancer Prostate

CARCINOMA PROSTATE

      The disorder occurs in older men (65 years) and history of obstruction to the urethra and the resultant frequency is of shorter duration. The patient may also present with pain due to spread desease to bones (pelvis, vertebra). On rectal examination, the prostate or a part of it feels hard and there is fixity due to spread to surrounding structures. The mucosa of the rectum may also be fixed to the prostate.

12.1 DIAGNOSIS

1.    An acid phosphatase(prostatic fraction) is elevated in cases with bony metastasis

2.    Xray examination of spine, pelvis and chest may reveal sclerotic secondaries

3.    A bone scan (99Tc) can reveal early secondaries

4.    An estimation of prostate specific antigen(PSA) is required

5.    A needle biopsy of the prstate may be required

12.2 TREATMENT

1.    A radical prostectomy is recommended in early cases.

2.    Hormonal-Stilbestrol or Honvan were given earlier to provide relief for bony pain. Cyproterone acetate, amino glutathemide and Flutemide have also been used with success in cases hormone dependent tumours.

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