STD Syphilis secondry & terciary lesions

Clinical Features

1.3.1 The typical Primary lesion in the male is a chancre on  the

externalr  genitalia. This is an indurated papule that  ulcerates

the edge and base continue to be indurated on palpation.

In  women, the primary sites are the labia and  cervix.  Regional

lymphadenopathy  appears (groin) a week later being painless  and

non-suppurative

1.3.2 SECONDARY LESIONS

Secondary lesions are many and include:

*  Generalised or localized mucocutaneous lesions

*  Generalised  non-tender lymphadenopathy and skin rash  can  be

   seen in most cases and occasionally papular lesions are seen.

*  Initial  lesions are  5-10 mm in diameter distributed  on  the

   trunk and legs

1.3.3 CONSTITUTIONAL SYMPTOMS

*  Include  fever,  sore throat, hoarsness, joint  pains,  weight

   loss and anorexia

*  Acute meningitis in 1-2% of patients

1.3.4 TERTIARY SYPHILIS (LATE SYPHILIS)

A   symptomatic  neurosyphilis  occurs  if  latent  syphilis   is

untreated and becomes symptomatic.

*  Manifestation of general paresis are due to parenchymal damage   

   in CNS and produce hyperactive reflexes and personality changes

*  Tabes  dorsalis  is due  to  demyelination  of  the  posterior

   columns and produce ataxia, paresthesia, hypeerflexia, bladder

   disturbance and Charcot's joints

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