Wednesday, October 24, 2012

MALIGNANT SKIN 2


SQUAMOUS CELL CARCINOMA (EPITHELIOMA)
These tumours can occur anywhere but usually occur on the exposed
parts  of the body (hand face).
 It also occurs in old burn scars, and sites of chronic irritation or irradiation.
 
CLINICAL FEATURES
The site of tumours formation starts as a hard nodule and develop
into an ulcer or cauliflower like growth.
Metastasis  occurs to the regional lymph nodes. These  are  hard
and soon get fixed to surrounding structure.
Histologic  examination  shows hyperchromatic  atypical  squamous
cells infiltrating the dermis forming "nests" or "pearls".
 
Treatment  is wide-excision with healthy margin or irradiation. 
The  involved lymph nodes need to be removed en block.

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