Friday, November 2, 2012

MALGNANT SKIN 3 melanomma


MELANOMA
Nearly 50% of melanomas arise in a mole. 
The development of malignancy should be suspected if there is any
one of the following changes observed in a coloured lesion:
   *  Increase in size
   *  A change in the outline of the mole
   *  A change in the colour of the mole
   *  Itching in the mole
   *  Bleeding from the mole
       -  It is believed that exposure to sunlight is responsible
          for these changes to occur
       -  Increased RISK is associated with those of fair skin. 
       -  The other RISK factors are socio-economic status and
          life style.
       -  Lesions in the upper extremity have a better PROGNOSIS
          than the lower extremity. 
       -  The worst PROGNOSIS are those of the
          head and
          neck or
          on the trunk
       -  Ulceration in the lesion is a bad sign. 
       -  Palpable lymph node are also a poor sign.
On  pathological  examination a more accurate  prognosis  can  be
given  on  histological examination since now the  depth  of  the
involvement of the skin can be identified according to the method
of Clark's .

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