Wednesday, February 6, 2013

MALIGNANT Breast Cancer 6


7. TREATMENT

The treatment modes available for Cancer Breast are:

   1.  Surgery
   2.  Radiotherapy
   3.  Chemotherapy
   4.  Hormonal therapy

*  Surgery is reserved for early cancer breast in cases of  stage
   I(T1 No) and stage II(T1, T2, N1).

   The operations in use today are:

   1.  Radical Mastectomy (Halstead)
       This  procedure is aimed at removing the whole  breast  the
       underlying  Pectoralis  major and minor  and  the  regional
       lymph  nodes  along  the  axillary  vein.   No   prosthatic
       reconcentration  is possible after the chest  wall  muscles
       have been removed.
   2.  Modified Radical Mastectomy (Patey's)
       In  this procedure all the structure accept the  Pectoralis
       Major are removed
   3.  Modified Radical Mastectomy (Maddon's)
       In  this procedure the pectoralis minor is divided but  not
       removed
   4.  Simple Mastectomy and clearance of lymphnodes from the
       axilla
       The  skin incision is eliptical and starts at over  rectus
       sheath and includes the nipple and the upper end is  above
       the  margin of the pectoralis major.  Both upper flap  are
       mobilised till the upper and lower limits of breast tissue
       are expanded.  The breast tissue (and nipple) are directed
       off  the pectoralis major.  The later end of the  incision
       allows excessing axillary lymph nodes.
   5.  Wide  local  excision of the tumour  with  preservation  of
       breast followed by radiation.
The  surgical procedure is dependent on the  surgeons  preference
and  the  clinical  stage of the disease. There is  a  trends  to
choose a less radical procedure among surgeons today.
*   Chemotherapy and hormone therapy (adjuvant therapy)is added to
    surgery in cases of Stage II.

It  has  been shown that chemotherapy has benefitted  both  those
with  nodes and those without nodes. 
Tomoxifen has also been  of benefit  to receptor positive and receptor poor tumours when  the
patient is over 50 years.
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