CARCINOMA OF THE GALLBLADDER
Carcinoma of the gallbladder accounts
for 4% of all carcinomas.
Approximately 80% of the patients in
most series are females
The
relationship between gallstones and carcinomas
has been
emphasized for many years.
Approximately 80% of the tumours are adenocarcinomas,
while the
remainder are undifferentiated or
squamous cell carcinomas. The
routes of metastases are spread-
*
Along the lymphatics
to pancreatic or
duodenal nodes,
localised
*
Involvement of venules and veins leades to the invation of the
liver
The presentation may be with signs and
symptoms of cholecystitis
and cholelithiasis.
Nearly half the patients are jaundice
and in most cases there is
a palpable right upper quadrant mass.
TREATMENT
Surgical treatment is achieved with
cholecystectomy and regional
lymphadenectomy.
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