*
White pulp consists of aggregation of
lymphocytes, plasma
cells and macrophages, it is
essentially lymphoid follicles
surrounding a central artery and is embedded in red pulp.
*
Red pulp is composed of thin walled splenic sinuses
filled
with blood surrounding the follicles of the white pulp.
*
In between the sinuses are plates or cords of cellular tissue.
*
Within the cordal network are erythrocytes and platelets.
Tagged
erythrocyte studies have shown
that normal cells
pass
quickly through
the organ and are
returned to the general
circulation.
*
Abnormal cells, however, are retained for considerable period
of time.
The large mass of retuculoendothelial
tissue in the adult spleen
serves
as an effecxtive filter to
separate out abnormal cells
from the circulation.
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