Tuesday, November 5, 2013

DUODENAL ULCER 1 causes clinical menifestations



Duodenal and Gastric ulcer are types of ulcers most often
seen in practice.

4. DUODENAL ULCER

4.1 Cause of duodenal ulcer is unknown.

*  Excessive acid peptic gastric secretion is probably one of the
   most importan etiolgoic factors.

*  Patients  have  increased  basal and  maximal  secretory  acid
   levels.

*  There  is  also evidence that reduction  of  duodenal  buffers
   (bile   and  pancreatic  juice)  lead  to  acidification   and
   ulceration.

4.2 CLINICAL MANIFESTATIONS

An active duodenal ulcer signals its presence by a symptom  often
described as "ulcer pain".

Pain is ofte vague located in the midepigastrium to the right  of
the midline described as a burning pain but may be a sensation of
pressure, cramp, discomfort or hunger.

*  The pain in an active duodenal ulcer is aggravated by fasting,
   thus, the patient must eat frequently.

*  Ingestion  of  plain water, milk or antacids give  prompt  and
   longer relief.

*  An  important trend of this ulcer is chronicity  and  seasonal
   variation of symptoms.

Other  symptoms may be bleeding (Haematemesis),  gastric  outflow
obstruction  and perforation.  These three are  complications  of
ulceration.

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