Wednesday, July 16, 2014

REGIONAL ENTERITIS Crohn's 3 treatment


OPERATIVE FINDINGS

The  early  changes observed are marked hyperemia,  dullness  and
fine  granularity  of  the  serosal  surface,  oedema  and   soft
thickening  of  the bowel wall with oedema of  the  corresponding
mesentery.

Intestinal  segements  involved  in  chronic  regional  enteritis
present a very characteristic appearance.

*  The  colour is dull, purple red and the wall is  thickened  to
   two or three times normal diameter.

*  Mesenteric fat is present over the serosa

*  Bowel wall is very firm, rubbery and incompressible.

*  segments are often adherent to adjacent loops

*  Loops may be matted together into a mass

*  Internal  fistulas  are frequently present in this  mass,  the
   mesentery is thickened, dull, rubberywith lymphnode masses  of
   upto 3 or 4 cm. in size.

The  proximal bowel is often dilated because of  the  obstruction
present in the diseased segment.

TREATMENT

There  is no curative therapy, systemic antibiotics are of  value
in the management of complications.

Nonabsorbable antibiotics, particularly  salicylazo-sulfapyridine
(Salazopyrin) exert a beneficial effect on the symptoms.

Treatment with corticosteroids have been disappointing.

SURGICAL INDICATIONS

In general, failure of medical therapy is the indication for  the
operative intervention.

Surgical  treatment  is used to correct  complications  that  are
themselves producing serious symptoms.

Simple  bypass  of  the diseased segment  and  resection  of  the
diseased segment are practiced.

BLIND LOOP

Stasis of intetinal contents in a blind loop e.g. diverticulitis
or  a  long loop in after gastric surgery  can  produce  symptoms
usually.

*  Malabsorbtion
*  Diarrhoea and
*  Anaemia

Symptoms  can be improved by antibiotics but surgical  correction
excising the blind loops can cure.

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