Wednesday, July 30, 2014

Small Intestines Carcoids cell of origin symptoms


 CARCINOID

The  cell of origin of carcinoids is the Kultschitzky  cells  and
the  cytoplasmic granules of the cell stain with silver  staining
and thus these lesions are also named "argentaffin tumors".

Carcinoid  tumours  can occur anywhere  in  the  gastrointestinal
tract  where the Kultschitzky cells occur from gastric cardia  to
anus.

Appendix is most frequently involved (46%)

*  followed by ileum (28%) and rectum (17%)

*  other locations are stomach, gallbladder, duodenum, jejunum.

Malignant Carcinoid Syndrome is manifested by cutaenous flushing:

*  hyper-peristalsis
*  diarrhoea
*  asthma and
*  haemodynamic alterations that may result in vesomotor collapse

These  effects  are produced by the vasoactive  products  of  the
carcinoid (5 hydroxytriptamine).

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